Successfully completing the S phase of each cell cycle ensures genome integrity.Impediment of DNA replication can lead to DNA damage and genomic disorders.In this study, we show a novel function for NDE1, whose mutations cause brain developmental disorders, in safeguarding the genome through S phase during early steps of neural progenitor fate rest
Transcriptome sequencing and De Novo analysis of Youngia japonica using the illumina platform.
Youngia japonica, a weed species distributed worldwide, has been widely used in traditional Chinese medicine.It is an ideal plant for studying the evolution of Asteraceae plants because of its short life history and abundant source.However, little is known about its evolution and genetic diversity.In this study, de novo transcriptome sequencing was
The Protection of Civilians: An Evolving Paradigm?
Whilst the protection of civilians (POC) in conflict has been a recurring feature of the humanitarian discourse the same has not been true in military doctrines, where the protection of civilians has long been cast in terms of arms bearers upholding their responsibilities under international humanitarian law (IHL).However, opportunities for YELLOW